Abstract

Extensive Study of Sentinel Biomarkers in Gynecologic Cancers Arena

Exosomes are a subclass of extracellular vesicles that are released by all cell types, including cancer cells. The cancer exosomes through intracellular communications convey malignant information in the form of proteins, lipids, and nucleic acids that can reprogram recipient cells. Thus, cancer progression and metastases seem to occur through cross-talk of cancer exosome and its micro-environment (cancer stromal cells, fibroblasts and neighboring tissues) [5]. Regarding the metastases, cancer exosomes play crucial roles. Invasion steps ofcancerseemtoinitiatefromcross-talkingwithcancercellsto their neighboring tissues containing cancer stromal tissues by exosomes. Concerning cancer exosomes involvement, exosomes play in specific aspects of tumor progression and metastases containing immune response[6]


Author(s):

Jaspreet Kuhal



Abstract | PDF

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