Received date: January 09, 2018; Accepted date: January 27, 2018; Published date: February 02, 2018
Citation: Zhao X, Li T, Liu J, Feng S, Wang H (2018) Recurrence Aortic Abdominal Dissection after Stent Grafting for Stanford Type B thoracic Dissection Case Report. Biomark J. 4:2. doi: 10.21767/2472-1646.100040
Acute aortic dissection remains the most common aortic catastrophe currently. It is significant to be on the alert for the recurrent aortic dissection. A 62-yearold woman with hypertension was admitted to the Emergency department with sudden intense back pain, profuse sweating and with the feeling of impending death for 3 hours. The surgeon of Peking University Shougang hospital conducted TEVAR in the first day after hospitalization and the back pain had lessened after the surgeon. The fourth day after hospitalization, the patient had Intermittent back pain. The recurrent dissection entry was found on the bottom of the thoracic artery stent-graft. The surgeon of Peking University Shougang hospital conducted the endovascular covered stent-graft repair of the abdominal aorta.
Type B thoracic dissection; Hypertension; Acute aortic dissection
A 62-year-old woman with hypertension was admitted to the Emergency Department with sudden intense back pain, profuse sweating and with the feeling of impending death for 3 hours. The pain was described as a constant and tearing feeling, which was not relieved by resting. She had a mild response to DanShen pill with sublingual administration in the pre-hospital setting. She was immediately sent for radiological examinations. Computed Tomography Angiography (CTA) findings indicated acute B thoracic dissection (DeBakey III) with a wide range of hematomas which ranging from aortic arch to aorta descendent (Figure 1A). Imagine showed that the dissection entry was found on the aortic arch just distal to the left subclavian artery orifice (Figure 1B). The patient had 5 years of irregularly monitored hypertension with family history of hypertension and had an allergy to penicillin. She was transferred to the Vascular Medicine intensive care unit. Medical therapies to control pain and sustain hemodynamic stability were performed with continuous infusion of Bucinnazine, Urapidil Hydrochloride and nitroprusside. The patient was hemodynamically stable, with a blood pressure of 121/70 mmHg and heart rate of 56 beats per minute. The electrocardiogram (ECG) showed signs of cardiac ischemia with the changes of T waves. The left brachial ankle pulse wave velocity (ba-PWV) of the case is 2138 cm/s and the right ba-PWV is 2018 cm/s.
Figure 1: (A, B) Computed tomography showed acute Stanford type B aortic dissection. The dissection entry was found on the aortic arch just distal to the left sub-clavian artery orifice. The initial computed tomography angiogram on the day of presentation demonstrating a descending thoracic aortic dissection with the true lumen identified by arrows.
The patient had uncontrolled hypertension, persistent pain. Therefore, emergency endovascular surgery was planned for repair of the complicated acute B thoracic dissection. The Thoracic Endovascular Aortic Repair (TEVAR) is considered a minimally invasive therapy, with lower operative morbidity and mortality rates than open surgical repair. The surgeon of Peking University Shougang hospital conducted TEVAR in the first day after hospitalization and the back pain had lessened after the surgeon. The final aortography revealed complete exclusion of the proximal entry site which maintained the blood supply to the abdominal aorta, and increased diameter of the true lumen. The Figure 2 showed the graft of the intraoperative cholangiography of the thoracic endovascular aortic repair. Computed tomography 2 days after the procedure showed that TEVAR was successful, resulting in expansion and patency of the true lumen with no endo-leak (Figure 3A and B). The fourth day after hospitalization, the patient had Intermittent back pain. Computed tomography angiography findings indicated recurrent abdominal aorta dissection with pleural effusion which eligible for the emergency interventional therapy. The recurrent dissection entry was found on the bottom of the thoracic artery stent-graft (Figure 4A and B). Comparing with the computed tomography imagine which conducted in the first day of the hospitalization (Figure 4C). The surgeon of Peking University Shougang hospital conducted the endovascular covered stent-graft repair of the abdominal aorta (Figure 5). The Figure 6 showed the graft of the intraoperative cholangiography of the abdominal endovascular aortic repair. However, the patient had Intermittent back pain once again in the sixth day after hospitalization. Repeated CTA findings indicated the absence of the recurrent aortic dissection (Figure 7A). The doctor reexamined computed tomography imagine before discharging from the hospital (Figure 7B).
Acute aortic dissection remains the most common aortic catastrophe currently [1-3]. The type of the acute B aortic dissection was divided into complicated and uncomplicated Acute Type B Aortic Dissection (ATBAD). Complicated acute type B aortic dissection was described as rupture, expansion of diameter on imaging during the admission, persistent pain, or clinical mal-perfusion leading to a deficit in cerebral, spinal, visceral, renal, or peripheral vascular territories at presentation or during initial hospitalization .
Patients with hypertension compounded by the stress and hemodynamic changes accompanying labor are predisposed to dissection as the aorta experiences increased shearing forces. To assess the influence of aortic stiffness on the extent of irreversible deformation and breaking stress of the human thoracic aorta, the team of Groenink M  conducted the research and found that Permanent deformation and rupture of the thoracic aorta following pressure overload are influenced by age, dispensability and collagen recruitment pressure. Because of the destruction of elastin leading to less strain-induced stiffening and predisposition to aortic dissection, the study of Nicholas R  suggest that hypertension is associated with a profound change in aortic wall mechanical properties possibly. Although it is remained that the computed tomography angiography is the top choice for imaging ATBAD, and magnetic resonance angiography is the second choice, these 2 modalities are static and present an arbitrary point in the cardiac cycle. Therefore, the dynamic natures of the dissection flap are unable to captured [7-9]. Recent publications acknowledge the importance of dynamic aortic evaluation in the treatment of aortic pathologies, especially aortic dissections [10-13]. In our study, we measured the brachial ankle pulse wave velocity of the both and found that the values are higher than the normal indicating that the patient had the aortic artery stiffness which might distribute to the process of the aortic dissection.
The characteristics of the case are Refractory Pain and Hypertension. A multivariable logistic regression model from Professor Santi Trimarchi  confirmed that recurrent and/or refractory pain or refractory hypertension was a predictor of inhospital mortality particularly when managed medically and their observations suggest that aortic intervention may be indicated in the intermediate-risk group. The back pain of our case was occurred third times during the hospitalization. It is significant to be on the alert for the recurrent aortic dissection.
On the other hand, the leading to degeneration of the medial arterial layer, which may occur with greater frequency during pregnancy as hormonal fluctuations influence elastic fibril organization and vascular integrity is explored. Takayasu aortitis is an uncommon, idiopathic inflammatory disease which mostly affects the aorta and its main branches. Besides the nonspecific inflammatory symptoms, Takayasu aortitis also could be complicated by either ischemic symptoms attributed to stenotic lesions or by aortic wall dilation, disruption, and dissection . However, the serum antibody was negative in this case. The follow-up management of the patient still is needed in the future.
We encountered a rare case of abdominal aortic dissection after TEVAR for complicated BAD, which were successfully repaired via emergency Stent Grafting. For patients complicated with type B aortic dissection, TEVAR is a preferable and less invasive treatment option which could seal the proximal entry site to maintain true lumen blood flow effectively.
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